What is Dupuytren’s of the Feet?

Dupuytren’s contracture of the feet, formally known as Ledderhose disease or plantar fibromatosis, is a condition in which the connective tissue (fascia) of the foot begins thickening. Initial symptoms generally include the development of a small, benign lump in the arch of the foot, known as plantar fibroma.

Ledderhose disease is often called Dupuytren’s of the feet because of its resemblance to Dupuytren’s disease of the hand (palmar fibromatosis), in which the fascia of the hand similarly thicken and develop lumps.

How does Ledderhose Disease of the feet impact patients?

While typical onset occurs around middle age or older, some younger adults may also develop the disease. Individuals who have Dupuytren’s (of the hands) or a family history of Ledderhose disease of the feet are also at a higher risk for developing the disease.

While there are many causes of Ledderhose disease of the feet, there are several known risk factors:




Liver Disease

Related Conditions

Foot Injury

  • Smoking
  • Diabetes
  • Epilepsy
  • Liver disease
  • Related medical conditions, including Peyronie’s, frozen shoulder, or knuckle pads
  • Injury or surgery to the foot

For many people, the initial lump(s) don’t have a noticeable effect. Over time, however, the lump(s) can grow and cause pain or discomfort—especially when sitting, walking, or running.

As the lumps grow, it can also become difficult to put on shoes. The skin on the underside of the foot may become tight and tender, the feet may swell, and the toes might curl under.

In earlier stages of Dupuytren’s contracture of the feet, there are some simple treatments that can help provide relief, including supportive shoes and orthotics, massage, stretching, ice, and over-the-counter anti-inflammatory medications (consult with your doctor prior to using these).

How is Ledderhose disease of the feet treated?

There are several ways to treat this condition. Here at Radiotherapy Centers of Kentuckiana, it is one of many that we treat with radiation therapy.

Learn more about the conditions we treat here.

Radiation therapy can be used both to reduce the size of growths and keep them from getting any bigger. This is vital, as the size of the lumps directly impacts the day-to-day lives of those with Dupuytren’s contracture of the feet, usually within several weeks of treatment. The benefits of radiation therapy are not just short-term, either. Those who are treated using radiation therapy are less likely to see their condition progress or to need surgery down the road.

If you have been diagnosed with Ledderhose disease and are experiencing discomfort or issues as a result, we would love to speak with you to see if radiation therapy could be a good treatment option. We have convenient locations in Jeffersonville, IL, and Louisville, KY. Call us today to set up a consultation.

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If you are referred for radiation therapy during your cancer care, you get to choose where to receive treatment. We are here to support and encourage you—call us today to schedule your first appointment with one of our radiation oncologists at the cancer center nearest to you.